GRAD > BIOL > 630

Molecular Evolution

Description:
This course provides a review of current knowledge in molecular evolution/evolutionary bioinformatics. It covers basic theories/principles for understanding evolutionary forces governing molecular variation and divergence as well as applications of these principles in important evolutionary topics. Basic theories/principles covered include 1) models of nucleotide change in DNA sequences and nucleotide substitution estimation; 2) phylogenic tree reconstruction with molecular data; and 3) neural mutation hypothesis and different methods of detecting natural selection. Topics then covered include molecular clocks, gene duplication and exon shuffling, concerted evolution of multigene families, evolution by transposition and horizontal gene transfer, genome organization and evolution, and comparative genomics.

Offered in:

TBA