The U54 Partnership holds an annual Request for Applications (RFA) during which, either Full or Pilot Projects are funded through our mechanism. Full Projects are awarded 3 years of funding while Pilot Projects are awarded 2 years of funding. The expectation for both Full and Pilot Projects is to pursue other sources of funding as a method of sustainability. Full Projects are encouraged to pursue external grants such as R01s or R25s from NIH. Pilot Projects are encouraged to pursue Full Project status with the Partnership as well as apply for external grants.