GRAD > BIOL > 627
Bacterial Physiology and Functional/Comparative Genomics
The objective of this course is to survey bacterial and archaeal structures, physiology, and underlying mechanisms. Key topics include bacterial cell composition and organization, the structure and function of bacterial cell components, assembly and polymerization of the bacterial cell, biosynthesis and energetics, bacterial cell growth, bacterial population growth, effect of key environmental parameters on cell growth, cell communication, the bacterial genome and its plasticity, coordination of metabolic reactions, regulation of gene expression at the operon and global levels, the bacterial cell cycle, control of bacterial growth rate, cellular differentiation, and physiological ecology of bacteria. The understanding of these bacterial properties is based in large part on functional and comparative microbial genomics; i.e., comparison of gene sets as the sequences become available, as well as recent biochemical, genetic, microscopic and physiological research advances.