UMass Boston

Exploring Limb Development and Regeneration

The McCusker Lab is focused on elucidating the molecular mechanisms underlying organ regeneration in adults, using the Axolotl (Ambystoma mexicanum) as a model organism. 

One of the long-term goals of the work conducted by the unit is to understand how regeneration naturally occurs in certain species so that we can apply these principles to safely unlock the regenerative potential in humans. In addition, research also has applications to other important areas of investigation, such as cancer and stem cell biology.